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Search Results for " transforming growth factor-β "

ターゲット

46

阻害剤

5

天然化合物

48

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T5197 BIBF0775 ALK , TGF-beta/Smad
BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
T2462 SB-505124 ALK , TGF-beta/Smad
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.
T4975 SM 16 ALK , TGF-beta/Smad
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
T2123 LY2109761 Autophagy , TGF-beta/Smad
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.
T4662 SJ000291942 TGF-beta/Smad
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
T1800 GW788388 GW 788388 ALK , TGF-beta/Smad
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
T1763 SB 525334 SB525334 ALK , TGF-beta/Smad
SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).
T1914 K02288 K 02288 ALK , TGF-beta/Smad
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
T1942 DMH-1 DMH1 ALK , Autophagy , TGF-beta/Smad
DMH-1 is a potent and selective BMP inhibitor.
T2510 Galunisertib LY2157299 TGF-beta/Smad
Galunisertib (LY2157299) is an orally available inhibitor of TGFβRI kinase (IC50: 56 nM) with potential antineoplastic activity.
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T1943 ML347 LDN 193719 ALK , TGF-beta/Smad
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
T2098 A 77-01 A77-01 ALK , TGF-beta/Smad
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
T4283 SRI-011381 TGF-beta/Smad
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T2109 SD-208 ALK5 Inhibitor V,SD208 TGF-beta/Smad
SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
T8730 BMS986260 TGF-beta/Smad
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
T5125 LY3200882 TGF-beta/Smad
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
T2048 LY-364947 LY 364947,HTS466284 MLK , Casein Kinase , TGF-beta/Smad , RIP kinase
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
T3031 A 83-01 ALK5 Inhibitor IV,A8301 ALK , TGF-beta/Smad
A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cult...
T1935 LDN193189 LDN-193189,DM-3189,LDN 193189 ALK , TGF-beta/Smad
LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6).
T8330 BIO-013077-01 TGF-beta/Smad
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
T1977 Dorsomorphin Compound C,BML-275 AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...
T1900 LDN-212854 LDN212854,BMP Inhibitor III ALK , TGF-beta/Smad
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
T7799 BMP signaling agonist sb4 SB 4 TGF-beta/Smad
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
T2273 ITD-1 TGF-beta/Smad
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
T1944 LDN-214117 ALK , TGF-beta/Smad
LDN-214117 is a potent and selective ALK2 inhibitor.
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T1726 SB-431542 SB 431542 ALK , TGF-beta/Smad
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio...
T6496 Vactosertib TEW-7197,EW-7197 ALK , TGF-beta/Smad
Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potentia...
T6337 RepSox ALK5 Inhibitor II,SJN 2511,E-616452 ALK , TGF-beta/Smad
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells.
T5129 SRI-011381 hydrochloride SRI-011381 hydrochloride [1629138-41-5(free base)] TGF-beta/Smad
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T4451 Estramustine phosphate sodium Ro 21-8837/001,Estramustine phosphate disodium Apoptosis , Microtubule Associated
Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T62483 CJJ300 TGF-beta/Smad
CJJ300 is a transforming growth factor-β (TGF-β) inhibitor (IC50 : 5.3 μM).CJJ300 inhibits TGF-β signaling by disrupting the formation of the TGF-β-TβR-I-TβR-II signaling complex.CJJ300 inhibits cell migration.
T76681 Fresolimumab GC1008 TGF-beta/Smad
Fresolimumab (GC1008) is a specific human anti-transforming growth factor β monoclonal antibody that binds to the active forms of human TGFβ1, TGFβ2, and TGFβ3 and can be used to study focal segmental glomerulosclerosis ...
T13604 CDDO-dhTFEA Others , NF-κB , Nrf2
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expressi...
T68333 Galunisertib Monohydrate
Galunisertib Monohydrate is a first-in-class transforming growth factor-β receptor type I inhibitor.
T60596 TGFβ-IN-1
TGFβ-IN-1 is an antitumor growth and metastasis agent by inhibiting the transforming growth factor β signaling pathway.
T79543 J27644 HDAC
J27644 is a potent HDAC (histone deacetylase) inhibitor that mitigates TGF-β (transforming growth factor beta)-induced pulmonary fibrosis [1].
T16464 Pelubiprofen COX
Pelubiprofen, an orally active non-steroidal anti-inflammatory drug (NSAID) belonging to the 2-arylpropionic acid family, selectively inhibits COX-2 activity alongside COX activity and the transforming growth factor-β ac...
T78585 Pentabromopseudilin
Pentabromopseudilin (PBrP), a marine antibiotic derived from Pseudomonas bromoutilis and Alteromonas luteoviolaceus, demonstrates antimicrobial, antitumor, and phytotoxic properties. It acts as a reversible, allosteric i...
T77076 Luspatercept
Luspatercept (ACE-536), a recombinant modified ActRIIB fusion protein, selectively binds to transforming growth factor β superfamily ligands, thereby enhancing erythrocyte production and advancing the maturation of eryth...
T63498 ALK5-IN-6
ALK5-IN-6 is a potent inhibitor of ALK5. ALK5-IN-6 has potential for TGF-β-related diseases and conditions, including but not limited to tumors, inflammatory diseases, fibrotic diseases, autoimmune diseases, etc.Among th...
T63114 ALK5-IN-7
ALK5-IN-7 is an effective inhibitor of ALK5. Transforming growth factor β (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation, and apoptosis through autocrine, paracri...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...

Compounds

BIBF0775
T5197
Synonym:
Target: ALK, TGF-beta/Smad
SB-505124
T2462
Synonym:
Target: ALK, TGF-beta/Smad
SM 16
T4975
Synonym:
Target: ALK, TGF-beta/Smad
LY2109761
T2123
Synonym:
Target: Autophagy, TGF-beta/Smad
SJ000291942
T4662
Synonym:
Target: TGF-beta/Smad
GW788388
T1800
Synonym: GW 788388
Target: ALK, TGF-beta/Smad
SB 525334
T1763
Synonym: SB525334
Target: ALK, TGF-beta/Smad
K02288
T1914
Synonym: K 02288
Target: ALK, TGF-beta/Smad
DMH-1
T1942
Synonym: DMH1
Target: ALK, Autophagy, TGF-beta/Smad
Galunisertib
T2510
Synonym: LY2157299
Target: TGF-beta/Smad
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
ML347
T1943
Synonym: LDN 193719
Target: ALK, TGF-beta/Smad
A 77-01
T2098
Synonym: A77-01
Target: ALK, TGF-beta/Smad
SRI-011381
T4283
Synonym:
Target: TGF-beta/Smad
SD-208
T2109
Synonym: ALK5 Inhibitor V,SD208
Target: TGF-beta/Smad
BMS986260
T8730
Synonym:
Target: TGF-beta/Smad
LY3200882
T5125
Synonym:
Target: TGF-beta/Smad
LY-364947
T2048
Synonym: LY 364947,HTS466284
Target: MLK, Casein Kinase, TGF-beta/Smad, RIP kinase
A 83-01
T3031
Synonym: ALK5 Inhibitor IV,A8301
Target: ALK, TGF-beta/Smad
LDN193189
T1935
Synonym: LDN-193189,DM-3189,LDN 193189
Target: ALK, TGF-beta/Smad
BIO-013077-01
T8330
Synonym:
Target: TGF-beta/Smad
Dorsomorphin
T1977
Synonym: Compound C,BML-275
Target: AMPK, Autophagy, TGF-beta/Smad
LDN-212854
T1900
Synonym: LDN212854,BMP Inhibitor III
Target: ALK, TGF-beta/Smad
BMP signaling agonist sb4
T7799
Synonym: SB 4
Target: TGF-beta/Smad
ITD-1
T2273
Synonym:
Target: TGF-beta/Smad
LDN-214117
T1944
Synonym:
Target: ALK, TGF-beta/Smad
IMM-H007
T9010
Synonym:
Target: Others, AMPK
SB-431542
T1726
Synonym: SB 431542
Target: ALK, TGF-beta/Smad
Vactosertib
T6496
Synonym: TEW-7197,EW-7197
Target: ALK, TGF-beta/Smad
RepSox
T6337
Synonym: ALK5 Inhibitor II,SJN 2511,E-616452
Target: ALK, TGF-beta/Smad
SRI-011381 hydrochloride
T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
Estramustine phosphate sodium
T4451
Synonym: Ro 21-8837/001,Estramustine phosphate disodium
Target: Apoptosis, Microtubule Associated
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
CJJ300
T62483
Synonym:
Target: TGF-beta/Smad
Fresolimumab
T76681
Synonym: GC1008
Target: TGF-beta/Smad
CDDO-dhTFEA
T13604
Synonym:
Target: Others, NF-κB, Nrf2
Galunisertib Monohydrate
T68333
Synonym:
Target:
TGFβ-IN-1
T60596
Synonym:
Target:
J27644
T79543
Synonym:
Target: HDAC
Pelubiprofen
T16464
Synonym:
Target: COX
Pentabromopseudilin
T78585
Synonym:
Target:
Luspatercept
T77076
Synonym:
Target:
ALK5-IN-6
T63498
Synonym:
Target:
ALK5-IN-7
T63114
Synonym:
Target:
(5E)-7-Oxozeaenol
T35438
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T75526 Chlorfortunone A
Chlorfortunone A, a novel sesquiterpenoid dimer isolated from the roots of Chloranthus fortunei, inhibits transforming growth factor (TGF)-β activity [1].
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat HEK293 Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPY-06247 TGF beta 3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1.
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-00413 Latent TGF beta 2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-01009 TGFBI Protein, Human, Recombinant (His) Human HEK293 Cells
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-03082 TGFBR2 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
TGFBR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P38438.
TMPY-03171 TGFBR2 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293 Cells
TGFBR2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.4 kDa and the accession number is H9YUL0.
TMPY-03649 TGFBR3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
TGFBR3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42.2 kDa and the accession number is Q03167-1.
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His) Canine HEK293 Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPY-02224 TGFBR3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TGFBR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is A0A0R4J097.
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600.
TMPY-00231 TGF beta 2 Protein, Canine, Recombinant (His) Canine HEK293 Cells
TGF beta 2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is A0A8C0RRP5.
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His) Rhesus HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is F6ZJW6.
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated Human HEK293 Cells
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812.
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPJ-00238 Lefty-A Protein, Human, Recombinant (His) Human HEK293 Cells
Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma...
TMPY-05810 TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293 Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173.
TMPY-05508 TGFBR2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173.
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36897-1.
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus Insect Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62.6 kDa and the accession number is P36897-1.
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1.
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPJ-01129 SMAD1 Protein, Human, Recombinant (GST) Human E. coli
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcripti...
TMPJ-00572 Vasorin Protein, Human, Recombinant (His) Human HEK293 Cells
Vasorin is a Type I membrane protein, which is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. The expression level of Vasorin can be down regulated during vessel repair af...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi) Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPY-03058 SLITL2/VASN Protein, Human, Recombinant (His) Human HEK293 Cells
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular...
TMPJ-01473 BMP-7 Protein, Human, Recombinant Human HEK293 Cells
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors...
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily....
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293 Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293 Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293 Cells
TGF beta 3 Protein, Human, Recombinant (hFc)
TMPY-06247
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
TMPY-00413
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
TGFBI Protein, Human, Recombinant (His)
TMPY-01009
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
Species: Human
Expression System: Baculovirus Insect Cells
TGFBR2 Protein, Mouse, Recombinant (His)
TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
TGFBR2 Protein, Rat, Recombinant (hFc)
TMPY-03082
Species: Rat
Expression System: HEK293 Cells
TGFBR2 Protein, Rhesus, Recombinant (hFc)
TMPY-03171
Species: Rhesus
Expression System: HEK293 Cells
TGFBR3 Protein, Human, Recombinant (His)
TMPY-03649
Species: Human
Expression System: Baculovirus Insect Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His)
TMPY-00229
Species: Canine
Expression System: HEK293 Cells
TGFBR3 Protein, Mouse, Recombinant (His)
TMPY-02224
Species: Mouse
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00622
Species: Cynomolgus
Expression System: HEK293 Cells
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00256
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Canine, Recombinant (His)
TMPY-00231
Species: Canine
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00772
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Rhesus, Recombinant (His)
TMPY-04577
Species: Rhesus
Expression System: HEK293 Cells
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00260
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05313
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00259
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05314
Species: Mouse
Expression System: HEK293 Cells
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
TMPJ-00771
Species: Mouse,Rat
Expression System: HEK293 Cells
Lefty-A Protein, Human, Recombinant (His)
TMPJ-00238
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc)
TMPY-01358
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Expression System: Baculovirus Insect Cells
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TMPJ-00333
Species: Mouse
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TMPJ-00334
Species: Mouse
Expression System: HEK293 Cells
SMAD1 Protein, Human, Recombinant (GST)
TMPJ-01129
Species: Human
Expression System: E. coli
Vasorin Protein, Human, Recombinant (His)
TMPJ-00572
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00329
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TMPK-00328
Species: Human
Expression System: HEK293 Cells
SLITL2/VASN Protein, Human, Recombinant (His)
TMPY-03058
Species: Human
Expression System: HEK293 Cells
BMP-7 Protein, Human, Recombinant
TMPJ-01473
Species: Human
Expression System: HEK293 Cells
ACVR2B Protein, Human, Recombinant (hFc & His)
TMPJ-00314
Species: Human
Expression System: HEK293 Cells
BMP-5 Protein, Human, Recombinant (hFc)
TMPY-00681
Species: Human
Expression System: HEK293 Cells
カタログ番号 製品名
L4100 TGF-beta/Smad Compound Library

184 compounds
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;